Tuesday, April 30, 2013

Google releases Glass intro video to help us all get started

New Project Glass YouTube channel starts up with an intro video for us all to enjoy, and wonder at

Despite being a long time out from the general consumer release of Project Glass, it's hard to deny that it's the hot ticket right now. The first units are in the hands of the lucky 'Explorers,' while the rest of us mere mortal, non-Glass wearing folks can simply look on in awe. 

We can at least get a look at the first in what's likely a series of tutorial videos for Glass released by Google, though. The new Project Glass YouTube channel has uploaded its first video, a getting started guide to Glass. We see a very quick, basic run through of how you operate it, and a look at the Google Now style card UI. It's exciting stuff, for sure, so if you're into Glass, be sure to keep an eye on the Project Glass YouTube channel. 

Source: Project Glass (YouTube)

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/iugPuJpKqJY/story01.htm

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Monday, April 29, 2013

Italian policemen shot near new gov't swearing-in

ROME (AP) ? In the very moments Italy's new coalition government was being sworn in, ending months of political paralysis in a country hoping to revive a bleak economy, a middle-aged unemployed bricklayer opened fire Sunday in the square outside the premier's office, seriously wounding two policemen, authorities said.

The alleged gunman from Calabria, a southern region plagued by joblessness and organized crime, told investigators he wanted to shoot politicians. But finding none in the square, he instead shot at Carabinieri paramilitary police.

A bullet pierced one of the policemen in the neck, passing through his spinal column, doctors said, adding it wasn't yet known if the 50-year-old officer would have any paralysis. The other one was shot in the leg and suffered a fracture.

The newly sworn in interior minister, Angelino Alfano, said a preliminary investigation indicated the shooting, which also slightly injured a pregnant bystander, amounted to a "tragic criminal gesture of a 49-year-old unemployed" man.

But the shooting was also a violent expression of social tensions in Italy, where unemployment is soaring, an increasing number of businesses are shutting their doors permanently and new political corruption scandals make headlines nearly every day.

Politicians described the attack as a disturbing call to fix Italy's economy.

"From what we understand, it's mainly personal problems, work, personal debts" that fueled the gunman's attack, said Guglielmo Epifani, a top official in Premier Enrico Letta's center-left Democratic Party.

Epifani said in a state TV interview that while the financial crisis has caused some to commit suicide, "this is the first time someone shoots to kill" someone else "in a place filled with innocent people."

"The symbolism is there," he said. The political world "must highlight its responsibility during the crisis before the country," he said.

In brief comments to reporters after paying a hospital visit to the more seriously wounded policeman, Letta said, "it is a moment in which each must do one's own duty."

The 46-year-old Letta will speak to Parliament on Monday, laying out his strategy to reduce joblessness while still sticking to the austerity measures needed to keep the eurozone's No. 3 economy from descending into a sovereign debt crisis. He will then face confidence votes needed to confirm his government.

Prosecutors identified the gunman as Luigi Preiti. Jobless, with a broken marriage and reportedly burdened by gambling debts he couldn't pay, Preiti had recently returned from Italy's affluent north, where he could no longer find work. He moved into his parents' home in Rosarno, a bleak Calabrian farm town where unemployment was already endemic before the last years of stagnation and recession sent youth unemployment soaring to nearly 40 percent nationwide.

His intended target was politicians, but with none in the square, he shot at the Carabinieri paramilitary police, Rome Prosecutor Pierfilippo Laviani told reporters, citing what he said Preiti told him when he questioned him.

Preiti, who was taken to the hospital for bruises, confessed to the shooting and didn't appear mentally unbalanced, Laviani said.

"He is a man full of problems, who lost his job, who lost everything," the prosecutor said. "He was desperate."

Mired in recession and suffering from soaring unemployment, Italy had been in political deadlock since an inconclusive February election. Social and political tensions have been running high among voters divided among a center-left bloc, conservative parties and an anti-establishment protest movement, which capitalized on public disgust with politicians to become Parliament's No. 3 force in its first national election bid.

The leader of the protest 5 Star Movement, comedian-turned-politician Beppe Grillo, has been criticized for inflammatory statements in the past, including saying during a campaign rally that the Parliament building could be a bombing target. He incessantly derides mainstream politicians as the root of Italy's ills.

"Words thrown like stones can become bullets," Rome's right-wing mayor, Gianni Alemanno, said after the shooting.

Grillo swiftly moved to distance what he describes as a grass-roots political movement from any calls to violence.

"The movement isn't at all violent," Grillo said.

Sunday was supposed to be a hopeful day with a new government, which, only a day earlier, was forged out of two bitter political enemies. Letta's forces, with strong roots in a former Communist party as well as centrist Christian Democrats, and media mogul Silvio Berlusconi's center-right bloc had agreed after days of negotiations to a kind of truce coalition intent on economic, political and electoral reform.

Then the sound of shots pierced the happy chatter in Piazza Colonna, near a busy shopping street shortly just as Letta and his new ministers were taking their oaths at the sumptuous hall of the Quirinal presidential palace, about a kilometer (half mile) away.

Sky TG24 TV and RAI state TV each showed a split screen, on one side, the chaos of panicked people fleeing the square; on the other side, smiling ministers taking the oath of office to work for the good of the nation.

"When I heard the first shot, I turned around and saw a man standing there, some 15 meters (50 feet) away from me. He held his arm out and I saw him fire another five, six shots," AP Television cameraman Fanuel Morelli, who was amazed at what appeared to be the man's deliberate calm, said. "He was firing at the second Carabiniere, who was about 4 meters (13 feet) in front of him."

The gunman was immediately wrestled to the ground by police outside Chigi Palace, which houses the premier's office. The new ministers arrived at the premier's office about 90 minutes later, for their first Cabinet meeting, some of them coming by foot as a way to reassure the public the area was safe.

The shooting panicked tourists and locals in the square on a rare sunny day at the end of a four-day holiday weekend.

A video surveillance camera on the Parliament building caught the attacker on film just before and during the shooting, Italian news reports said. In the film, the shooter is seen walking at a steady pace along a narrow street that leads from near Parliament's lower house to the edge of Colonna Square, where police officers appear to have stopped him to ask where he was going. Shortly after that, the man begins firing, the surveillance camera showed, according to the reports.

Alfano said Preiti wanted to kill himself after the shooting, but ran out of bullets. He said six shots were fired in all. Laviani said the assailant had obtained his weapons on the black market. Sky reported that Preiti had taken a train to Rome from Calabria on Saturday, and that police found his car parked at a southern train station.

The interior minister said security was immediately stepped up near key venues in the Italian capital, but added authorities were not worried about possible related attacks.

"Our initial investigation indicates the incident is due to an isolated gesture, although further investigations are being carried out," he said.

The ministers were kept briefly inside for security reasons until it was clear there was no immediate danger.

Preiti's uncle, interviewed by Sky, said the alleged gunman had moved back to his parents' home in Calabria because he could no longer find work as a bricklayer. "He was a great worker. He could build a house from top to bottom," the uncle, Domenco Preiti, said.

The shooting revived ugly memories of the 1970s and 1980s in Italy, when domestic terrorism plagued the country during a time of high political tension between right-wing and left-wing blocs.

President Barack Obama wished the new Italian government well. The White House press office said Obama was looking forward to working closely with Letta's government "to promote trade, jobs, and growth on both sides of the Atlantic and tackle today's complex security challenges."

There was no direct reference to the shooting in the White House statement.

Trying to renew Italy's largely discredited political class, Letta brought many political newcomers into his Cabinet, including an eye surgeon who is a Congo native, and now is Italy's first black minister, in charge of integration issues involving the growing immigrant population.

But the new premier also sought to reassure European central bankers and EU officials anxious that his government will stay the austerity course set by Mario Monti, who replaced Berlusconi in 2011 to save Italy from sliding deeper into the sovereign debt crisis. Letta picked the Italian central bank's director general, who formerly worked at the International Monetary Fund, to hold the crucial economy ministry.

While the coalition's bitter rival blocs might be enjoying a truce, relations could deteriorate. Berlusconi has insisted that the government's first act should be undoing a highly unpopular property tax Monti established to help the state's coffers.

Source: http://news.yahoo.com/italian-policemen-shot-near-govt-swearing-201756998.html

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Sunday, April 28, 2013

Bulgaria's center right on track for election win: poll

SOFIA (Reuters) - Bulgaria's center-right GERB party is on course for election victory on May 12 despite resigning from the government after mass protests against low living standards in February, a poll showed on Sunday.

The state-funded NPOC survey put ex-premier Boiko Borisov's GERB at 23.6 percent and the Socialists at 17.7 percent. On this basis, however, a hung parliament looked likely since a party needs over 43 percent of votes for a majority.

Tens of thousands of people took to the streets in the European Union's poorest country in anger over corruption, rising unemployment and high utility bills, prompting the resignation of Borisov's government.

Analysts say the unrest galvanized GERB supporters while protesters failed to form a single political group to challenge its position. The Socialists have failed to gain from the discontent since may protesters were unhappy with the whole political class, not just GERB.

Support for GERB was also largely unaffected by charges against four senior interior ministry officials for mishandling wiretapping equipment and data, which prosecutors said could have resulted in illegal surveillance of politicians and businessmen.

The nationwide survey, conducted between April 19 and 25, showed backing for the ethnic Turkish MRF party fell slightly to 6.0 percent in April from 6.5 percent a month earlier.

The biggest beneficiary from the nationwide protests in February was the far-right Attack party, whose support was 4.9 percent in April, up from 1.2 percent two months ago.

Attack's pledges of nationalizations, higher taxes for the rich and to revoke foreign concessions for gold and water have alarmed some investors.

(NPOC is state-owned, Gallup is an independent polling agency)

(Reporting by Angel Krasimirov; Editing by Robin Pomeroy)

Source: http://news.yahoo.com/bulgarias-center-track-election-win-poll-133942976.html

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Legal Theory Blog: Materni on Criminal Justice

Mike C. Materni (Harvard Law School) has posted Criminal Punishment and the Pursuit of Justice (2 Br. J. Am. Leg. Studies 263 (2013)) on SSRN. Here is the abstract:
    Since the beginning of recorded history societies have punished offenders while at the same time trying to justify the practice on moral and rational grounds and to clarify the relationship between punishment and justice. Traditionally, deontological justifications, utilitarian justifications, or a mix of the two have been advanced to justify the imposition of punishment upon wrongdoers. In this article, I advance a new conceptual spin on the mixed theorist approach to criminal punishment ? one that can hopefully resonate not just among legal philosophers, but also among ordinary citizens,i.e. the people who are most affected by the criminal law. Distancing myself from previous scholarship, which has used utilitarian arguments to point out the shortcomings of retributivism and vice-versa, on the one hand I attack the philosophical foundations of retributivism (currently the predominant rationale for punishment) on deontological grounds; on the other hand I attack the consequentialist rationales on consequentialist grounds. Concluding that neither approach ? as they all fail under their own standards ? is sufficient per se to justify criminal punishment in a liberal democracy, I argue that a mixed theory approach, which is usually presented as a matter of preference, is instead a matter of necessity if we want a criminal justice system that, while still not perfect, can be defended on both rational and moral grounds. In this sense, retributive considerations are meant to serve as the normative check on a system that aims at rationality and efficiency, and it is thus strongly utilitarian in character. I conclude by arguing that something more than punishment is required if we want to implement a system that really pursues justice, and I suggest that a path worth exploring in that regard is the one laid down by restorative justice. If nothing else, hopefully my blistering attack on retributivism will serve the purpose of rekindling a debate that seems to have accepted the dominance of retributivist positions.

Source: http://lsolum.typepad.com/legaltheory/2013/04/materni-on-criminal-justice.html

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Exclusive: Boston bomb suspects' parents retreat to village, cancel U.S. trip

By Maria Golovnina

UNDISCLOSED LOCATION IN NORTH CAUCASUS, Russia (Reuters) - The parents of the Boston Marathon bombing suspects have retreated to a village in southern Russia to shelter from the spotlight and abandoned plans for now to travel to the United States, the father of the suspects told Reuters on Sunday.

Speaking in the garden of a large house, Anzor Tsarnaev said he believed he would not be allowed to see his surviving son Dzhokhar?, who was captured and has been charged in connection with the April 15 bomb blasts that killed three people and wounded 264.

"Unfortunately I can't help my child in any way. I am in touch with Dzhokhar's and my own lawyers. They told me they would let me know (what to do)," Tsarnaev said in an interview in the village where he relocated with the suspects' mother.

He agreed to the face-to-face meeting on condition that the village's location in the North Caucasus, a string of mainly Muslim provinces in southern Russia, not be disclosed.

"I am not going back to the United States. For now I am here. I am ill," said Tsarnaev, pacing nervously in the garden at sunset in the quiet village set in rolling hills and surrounded by cow pastures.

His face gaunt and tired, Tsarnaev said he suffered from high blood pressure and a heart condition.

Tsarnaev had said in the North Caucasus province of Dagestan on Thursday that he planned to travel to the United States to see Dzhokhar and bury his elder son, Tamerlan, who was killed during a manhunt four days after the bombings.

In Sunday's interview he said he had decided to move away from the family home in Dagestan to the new location because he wanted to keep a low profile.

Dressed in a black shirt and black trousers, he passionately defended his sons' innocence, saying they had nothing to do with Islamist extremists.

"I feel hopeless. We are simple people. We are trying to understand. We are attacked from all sides," he said, clutching his head in despair.

"I don't know whether I should talk or stay silent. I don't want to harm my child. ... We are used to all sorts of things here but we didn't expect this from the United States."

He and other members of the family believe a man shown on television being led naked into a police car the night of the shootout was Tamerlan, and that the blurry footage, still widely available on YouTube, proves Tamerlan was captured alive. Boston police say Tamerlan was killed in a shootout, and the man seen being led into the car was a bystander who was briefly detained.

Anzor Tsarnaev said he raised the issue with U.S. officials who visited him earlier in the week in his home in Dagestan.

"I asked them: 'I saw my child alive, he was being put into a police vehicle alive and healthy. How come media said he was killed?' They were shocked themselves," the father said.

CAUCASUS ROOTS

The Tsarnaevs are ethnic Chechens who lived in the Central Asian country of Kyrgyzstan and in Dagestan before emigrating to the United States with their children. The parents returned to Dagestan two years ago, and Tamerlan spent the first half of 2012 there.

The suspects' mother, Zubeidat, was with Anzor Tsarnaev in the village but did not wish to speak.

"She is ill, she is shocked, she is depressed. She lost her children," Tsarnaev said. The couple are divorced but have stayed together.

Although the Tsarnaev brothers have roots in Dagestan and neighboring Chechnya, neither had spent much time there until Tamerlan returned to Dagestan last year for six months.

During his interview, Anzor Tsarnaev denied Tamerlan had any contact with militants during his stay, painting an idyllic picture of his son's visit to his ancestral homeland.

"When he came to stay here, he was a good boy. He read books, (Leo) Tolstoy, (Alexandre) Dumas and thick English language books. He would wake up late and read all day, late into the night," he said.

"Sometimes we went to the mosque. We went to see our relatives, in Dagestan, in Chechnya. We visited a lot of households, it was a nice atmosphere."

Tsarnaev said he had to force his son to return to the United States to complete his U.S. citizenship application after Tamerlan tried to convince his family to allow him to stay in Dagestan for good.

"I told him: 'No, you have to go back to obtain your U.S. citizenship'. I forced him to go back. I thought it was the right thing to do. I shouldn't have done that," he said with a pained expression on his face.

The father said he had no hope that Tamerlan's body would be released by the U.S. authorities to be buried in his homeland.

"They won't give us his body," he said, his voice breaking with emotion. "We wont be able to bury him in our land."

(Writing by Maria Golovnina)

Source: http://news.yahoo.com/exclusive-boston-bomb-suspects-father-abandons-plan-return-160819875.html

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Saturday, April 27, 2013

Gabby Douglas Literally Flips Out For McDonald's

Source: http://www.thehollywoodgossip.com/2013/04/gabby-douglas-literally-flips-out-for-mcdonalds/

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Scientists discover new way protein degradation is regulated

Apr. 25, 2013 ? Proteins, unlike diamonds, aren't forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University and the Howard Hughes Medical Institute have identified a new way that the cell's protein recycler, the proteasome, takes care of unwanted and potentially toxic proteins, a finding that has implications for treating muscle wasting, neurodegeneration and cancer.

The consensus among scientists has been that the proteasome is constantly active, chewing up proteins that have exceeded their shelf life. A mounting body of evidence now suggests that the proteasome is dynamically regulated, ramping up its activity when the cell is challenged with especially heavy protein turnover. The researchers, postdoctoral associate Park F. Cho-Park and Hermann Steller, head of the Strang Laboratory of Apoptosis and Cancer Biology at Rockefeller, have shown that an enzyme called tankyrase regulates the proteasome's activity. In addition, Cho-Park and Steller demonstrate that a small molecule called XAV939, originally identified by scientists at Novartis who developed it as therapeutic for colon cancer, inhibits tankyrase and blocks the proteasome's activity. The research is reported in today's issue of the journal Cell.

"Our findings have tremendous implications for the clinic since it gives a new meaning to an existing class of small-molecule compound," says Steller, Strang Professor at Rockefeller and an investigator at HHMI. "In particular, our work suggests that tankyrase inhibitors may be clinically useful for treating multiple myeloma."

Tankyrase was originally identified in the late 1990s by Rockefeller's Titia de Lange and her colleagues in the Laboratory for Cell Biology and Genetics, who showed that it plays a role in elongating telomeres, structures that cap and protect the ends of chromosomes. In a series of experiments in fly and human cells, Cho-Park and Steller discovered that tankyrase uses a process called ADP-ribosylation to modify PI31, a key factor that regulates the activity and assembly of proteasome subunits into the active complex called 26S. By promoting the assembly of more 26S particles, cells under stress can boost their ability to break down and dispose of unwanted proteins.

The proteasome is currently a target for developing cancer therapeutics. The FDA has approved Velcade, a proteasome inhibitor, for the treatment of multiple myeloma and mantle cell lymphoma. However, patients on Velcade can experience peripheral neuropathy or become resistant to the drug.

Multiple myeloma cells need increased proteasome activity to survive. Preliminary data from Cho-Park and Steller show that XAV939 can block the growth of multiple myeloma cells by inhibiting the assembly of additional proteasomes without affecting the basal level of proteasomes in the cell. This selective targeting may mean fewer side effects for patients. "Drugs, such as XAV939, that inhibit the proteasome through other mechanisms than Velcade may have significant clinical value," says Steller.

The findings by Cho-Park and Steller also link, for the first time, metabolism and regulation of the proteasome. Sometimes the proteasome digests too much protein, which can lead to loss of muscle, says Steller.

"This discovery reveals fundamental insights into protein degradation, a process important for normal cell biology, and a key factor in disorders such as muscle wasting and neurodegeneration," said Stefan Maas of the National Institutes of Health's National Institute of General Medical Sciences, which partly supported the study. "Intriguingly, the findings also enlighten ongoing research on cancer therapies, exemplifying the impact of basic research on drug development."

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The above story is reprinted from materials provided by Rockefeller University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Park?F. Cho-Park, Hermann Steller. Proteasome Regulation by ADP-Ribosylation. Cell, 2013; 153 (3): 614 DOI: 10.1016/j.cell.2013.03.040

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/IYiMY7-r1zk/130426114644.htm

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